Alvesco®

INHALED CORTICOSTEROIDS

INHALED CORTICOSTEROID (ICS)

  • Class

    • Inhaled corticosteroid (ICS)

  • Active ingredient

    • Ciclesonide

  • Device

  • Age

    • 6 +
  • Typical use

    • Asthma
      Initial controller

    Asthma management principles
    • COPD (off-label)
      in addition to a dual bronchodilation (LAMA/LABA) when exacerbating

    COPD management principles
  • Marketed strength

    • 100 mcg
    • 200 mcg
  • Number of doses

    • 120 doses
  • Dose indicator

    • No
  • Usual adult dosage

    • Low | 200 mcg – 1 inh QD
      Medium | 200 mcg – 2 inh QD
      High | 200 mcg – 2 inh BID
      Maximum daily dose: 800 mcg

    ICS dosing
  • Usual pediatric dosage

    • 1-11 years
      Low
      | 100 mcg – 1 inh QD
      Medium | 200 mcg – 1 inh QD

      12-17 years

      See adult dosage

    ICS dosing
  • Required inspiratory flow

    • < 30 L/min 
      Zero internal resistance (R0)

    Inspiratory flows
  • Public coverage

    • All provinces | Open/Regular Benefit

  • Advantages

    • Once daily dosing (at low or medium doses)
    • Less local side effects
    • Suitable for low inspiratory flows
    • No synchronism required with a spacer
    • Less growth reduction in children
  • Disadvantages

    • Cumbersome with a spacer
    • Impossible to know when empty
    • Round mouthpiece may be difficult to insert in a spacer
    • Contain greenhouse gases
    Side Effects

Product monograph

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