Combivent®

COMBINATIONS (DUO)

SHORT-ACTING MUSCARINIC ANTAGONIST + SHORT-ACTING BETA-2 AGONIST (SAMA + SABA)

  • Class

    • Short-acting muscarinic antagonist (SAMA)
      Short-acting beta-2 agonist (SABA)

  • Active ingredient

    • Ipratropium bromide


    • Salbutamol (as sulfate)

  • Device

  • Age

    • 18 +
  • Typical use

    • Asthma
      no common use

    Asthma management principles
    • COPD
      no common use

    COPD management principles
  • Marketed strength

    • 20/100 mcg
  • Number of doses

    • 120 doses
  • Dose indicator

    • Yes | Indicator
  • Usual adult dosage

    • 1 inh QID + PRN
      Maximum daily dose: 6 inh

  • Usual pediatric dosage

    • -

  • Required inspiratory flow

    • < 30 L/min
      Zero internal resistance (R0)

    Inspiratory flows
  • Public coverage

    •  All provinces expect AB – ON – QC | Open/Regular Benefit
      AB – ON – QC | Not a Benefit

  • Advantages

    • Suitable for low inspiratory flows
    • Impossible to take empty (locking mechanism)
    • Can be used with a spacer
  • Disadvantages

    • Short duration of action

    • Cartridge insertion difficult
    • Base turn for loading difficult
    • Risk of spraying the face if cap opened before rotating the base
    • Occasional cough without spacer
    • Synchronism required
    Side effects

Product monograph

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