Symbicort®

COMBINATIONS (DUO)

INHALED CORTICOSTEROID + LONG-ACTING BETA-2 AGONIST (ICS + LABA)

  • Class

    • Inhaled corticosteroid (ICS)
      Long-acting beta-2 agonist (LABA)

  • Active ingredient

    • Budesonide


    • Formoterol fumarate dihydrate

  • Device

  • Age

    • 12 +
  • Typical use

    • Asthma
      uncontrolled on low dose ICS (regular intake) or initial treatment (PRN intake)

    Asthma management principles
    • COPD
      in addition to a LAMA, when exacerbating on dual bronchodilation (LAMA/LABA)

    COPD management principles
  • Marketed strength

    • 100/6 mcg
    • 200/6 mcg
  • Number of doses

    • 120 doses
  • Dose indicator

    • Yes | Indicator
  • Usual adult dosage

    • PRN | 200/6 mcg – 1 inh PRN
      Low | 100/6 mcg – 2 inh BID
      Medium | 200/6 mcg – 2 inh BID
      High | 200/6 mcg – 3-4 inh BID
      Maximum daily dose: 8 inh

    ICS dosing
  • Usual pediatric dosage

    • 6-11 years
      Low | 100/6 mcg – 1 inh QD
      Medium | 200/6 mcg – 1 inh BID

       

      12-17 years
      See adult dosage

    ICS dosing
  • Required inspiratory flow

    • > 30 - 60 L/min
      Medium internal resistance (R3)

    Inspiratory flows
  • Public coverage

    • MN | Open/Regular Benefit
      All provinces except MN | Restricted Benefit with criteria 

    Provincial coverage criteria
  • Advantages

    • May be taken as a rescue medication

    • Same inhaler for the regular treatment and the asthmatic action plan

  • Disadvantages

    • BID dosing

    • High number of inhalations for high ICS dose

    Side effects

Product monograph

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