Wixela®
COMBINATIONS (DUO)
INHALED CORTICOSTEROID + LONG-ACTING BETA-2 AGONIST (ICS + LABA)
COMBINATIONS (DUO)
INHALED CORTICOSTEROID + LONG-ACTING BETA-2 AGONIST (ICS + LABA)
Class
Inhaled corticosteroid (ICS)
Long-acting beta-2 agonist (LABA)
Active ingredient
Fluticasone propionate
Salmeterol (as the xinafoate salt)
Device
Age
Typical use
Asthma
uncontrolled on low dose ICS
COPD
in addition to a LAMA, when exacerbating on dual bronchodilation (LAMA/LABA)
Marketed strength
Number of doses
Dose indicator
Usual adult dosage
Low | 100/50 mcg – 1 inh BID
Medium | 250/50 mcg – 1 inh BID
High | 500/50 mcg – 1 inh BID
Usual pediatric dosage
6-11 years
Low | 100/50 mcg – 1 inh QD
Medium | 250/50 mcg – 1 inh QD
12-17 years
See adult dosage
Required inspiratory flow
> 30 - 60 L/min
Medium internal resistance (R3)
Public coverage
MN | Open/Regular Benefit
All provinces except MN | Restricted Benefit with criteria
Advantages
Disadvantages
Product monograph
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